TY - JOUR
T1 - The synthesis and receptor binding affinities of DDD-016, a novel, potential, atypical antipsychotic
AU - Bandyopadhyaya, Achintya K.
AU - Rajagopalan, Desikan R
AU - Rath, Nigam
AU - Herrold, Amy
AU - Rajagopalan, Raghavan
AU - Napier, T. Celesete
AU - Tedford, Clark E.
AU - Rajagopalan, Parthasarathi
N1 - A new pentacyclic compound, DDD-016 (10d) was designed and synthesized as a potential antipsychotic and screened for binding affinity in a broad panel of over 80 CNS and other receptors, monoamine transporters, and ion channels. The resulting receptor binding profile of DDD-016 is consistent with that of an
PY - 2012/5/7
Y1 - 2012/5/7
N2 - A new pentacyclic compound, DDD-016 (10d) was designed and synthesized as a potential antipsychotic and screened for binding affinity in a broad panel of over 80 CNS and other receptors, monoamine transporters, and ion channels. The resulting receptor binding profile of DDD-016 is consistent with that of an improved atypical antipsychotic candidate.
AB - A new pentacyclic compound, DDD-016 (10d) was designed and synthesized as a potential antipsychotic and screened for binding affinity in a broad panel of over 80 CNS and other receptors, monoamine transporters, and ion channels. The resulting receptor binding profile of DDD-016 is consistent with that of an improved atypical antipsychotic candidate.
UR - https://doi.org/10.1039/C2MD00311B
U2 - 10.1039/C2MD00311B
DO - 10.1039/C2MD00311B
M3 - Article
VL - 3
JO - MedChemComm
JF - MedChemComm
ER -