The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21.

Richard J. Auchus; A. Sampath Kumar; C. Andrew Boswell; Manisha K. Gupta; Kristen Bruce; Nigam P. Rath; Douglas F. Covey

doi:10.1016/S0003-9861(02)00491-5

The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21.

Richard J. Auchus
, A. Sampath Kumar
, C. Andrew Boswell
, Manisha K. Gupta
, Kristen Bruce
, Nigam P. Rath
, Douglas F. Covey

University of Missouri-St. Louis

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Archives of Biochemistry and Biophysics
Volume	409
DOIs	https://doi.org/10.1016/S0003-9861(02)00491-5
State	Published - Jan 1 2003

Disciplines

Biochemistry
Molecular Biology

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title = "The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21.",

author = "Auchus, \{Richard J.\} and Kumar, \{A. Sampath\} and Boswell, \{C. Andrew\} and Gupta, \{Manisha K.\} and Kristen Bruce and Rath, \{Nigam P.\} and Covey, \{Douglas F.\}",

note = "Human cytochrome P450c17 (17α-hydroxylase, 17,20-lyase) (CYP17) and cytochrome P450c21 (21-hydroxylase) (CYP21) differ by only 14 amino acids in lengt...",

year = "2003",

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doi = "10.1016/S0003-9861(02)00491-5",

language = "American English",

volume = "409",

journal = "Archives of Biochemistry and Biophysics",

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T1 - The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21.

AU - Auchus, Richard J.

AU - Kumar, A. Sampath

AU - Boswell, C. Andrew

AU - Gupta, Manisha K.

AU - Bruce, Kristen

AU - Rath, Nigam P.

AU - Covey, Douglas F.

N1 - Human cytochrome P450c17 (17α-hydroxylase, 17,20-lyase) (CYP17) and cytochrome P450c21 (21-hydroxylase) (CYP21) differ by only 14 amino acids in lengt...

PY - 2003/1/1

Y1 - 2003/1/1

UR - https://www.sciencedirect.com/science/article/pii/S0003986102004915

U2 - 10.1016/S0003-9861(02)00491-5

DO - 10.1016/S0003-9861(02)00491-5

M3 - Article

VL - 409

JO - Archives of Biochemistry and Biophysics

JF - Archives of Biochemistry and Biophysics

ER -

The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21.

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