The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21.

Richard J. Auchus; A. Sampath Kumar; C. Andrew Boswell; Manisha K. Gupta; Kristen Bruce; Nigam P. Rath; Douglas F. Covey

doi:10.1016/S0003-9861(02)00491-5

The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21.

Richard J. Auchus, A. Sampath Kumar, C. Andrew Boswell, Manisha K. Gupta, Kristen Bruce, Nigam P. Rath, Douglas F. Covey

University of Missouri-St. Louis

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Archives of Biochemistry and Biophysics
Volume	409
DOIs	https://doi.org/10.1016/S0003-9861(02)00491-5
State	Published - Jan 1 2003

Disciplines

Biochemistry
Molecular Biology

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title = "The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21.",

author = "Auchus, {Richard J.} and Kumar, {A. Sampath} and Boswell, {C. Andrew} and Gupta, {Manisha K.} and Kristen Bruce and Rath, {Nigam P.} and Covey, {Douglas F.}",

note = "Human cytochrome P450c17 (17α-hydroxylase, 17,20-lyase) (CYP17) and cytochrome P450c21 (21-hydroxylase) (CYP21) differ by only 14 amino acids in lengt...",

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doi = "10.1016/S0003-9861(02)00491-5",

language = "American English",

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T1 - The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21.

AU - Auchus, Richard J.

AU - Kumar, A. Sampath

AU - Boswell, C. Andrew

AU - Gupta, Manisha K.

AU - Bruce, Kristen

AU - Rath, Nigam P.

AU - Covey, Douglas F.

N1 - Human cytochrome P450c17 (17α-hydroxylase, 17,20-lyase) (CYP17) and cytochrome P450c21 (21-hydroxylase) (CYP21) differ by only 14 amino acids in lengt...

PY - 2003/1/1

Y1 - 2003/1/1

UR - https://www.sciencedirect.com/science/article/pii/S0003986102004915

U2 - 10.1016/S0003-9861(02)00491-5

DO - 10.1016/S0003-9861(02)00491-5

M3 - Article

VL - 409

JO - Archives of Biochemistry and Biophysics

JF - Archives of Biochemistry and Biophysics

ER -

The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21.

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