Synthesis, Molecular Structure, and Validation of Metalloprobes for Assessment of MDR1 P-Glycoprotein-Mediated Functional Transport

Jothilingam Sivapackiam; Scott E. Harpstrite; Julie L. Prior; Hannah Gu; Nigam P. Rath; Vijay Sharma

doi:10.1039/C002361B

Synthesis, Molecular Structure, and Validation of Metalloprobes for Assessment of MDR1 P-Glycoprotein-Mediated Functional Transport

Jothilingam Sivapackiam
, Scott E. Harpstrite
, Julie L. Prior
, Hannah Gu
, Nigam P. Rath
, Vijay Sharma

University of Missouri-St. Louis

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Dalton Transactions
Volume	39
DOIs	https://doi.org/10.1039/C002361B
State	Published - Jan 1 2010

Disciplines

Pharmacology
Inorganic Chemistry
Molecular Biology

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10.1039/C002361BLicense: Unspecified

Cite this

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title = "Synthesis, Molecular Structure, and Validation of Metalloprobes for Assessment of MDR1 P-Glycoprotein-Mediated Functional Transport",

author = "Jothilingam Sivapackiam and Harpstrite, \{Scott E.\} and Prior, \{Julie L.\} and Hannah Gu and Rath, \{Nigam P.\} and Vijay Sharma",

note = "The human genome is known to consist of 49 ATP-binding cassette (ABC) transporter genes. Among these ABC proteins, overexpression of multidrug resistance (MDR1) P-glycoprotein (Pgp/ABCB1) is the best characterized barrier to successful chemotherapeutic treatments, impacts pharmacokinetics of numerous recognized dru",

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doi = "10.1039/C002361B",

language = "American English",

volume = "39",

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T1 - Synthesis, Molecular Structure, and Validation of Metalloprobes for Assessment of MDR1 P-Glycoprotein-Mediated Functional Transport

AU - Sivapackiam, Jothilingam

AU - Harpstrite, Scott E.

AU - Prior, Julie L.

AU - Gu, Hannah

AU - Rath, Nigam P.

AU - Sharma, Vijay

N1 - The human genome is known to consist of 49 ATP-binding cassette (ABC) transporter genes. Among these ABC proteins, overexpression of multidrug resistance (MDR1) P-glycoprotein (Pgp/ABCB1) is the best characterized barrier to successful chemotherapeutic treatments, impacts pharmacokinetics of numerous recognized dru

PY - 2010/1/1

Y1 - 2010/1/1

UR - http://pubs.rsc.org/en/content/articlepdf/2010/dt/c002361b

U2 - 10.1039/C002361B

DO - 10.1039/C002361B

M3 - Article

VL - 39

JO - Dalton Transactions

JF - Dalton Transactions

ER -

Synthesis, Molecular Structure, and Validation of Metalloprobes for Assessment of MDR1 P-Glycoprotein-Mediated Functional Transport

Disciplines

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