Synthesis and Kinetic Evaluation of Cyclophostin and Cyclipostins Phosphonate Analogs As Selective and Potent Inhibitors of Microbial Lipases

Vanessa Point; Raj K. Malla; Sadia Diomande; Benjamin P. Martin; Vincent Delorme; Frederic Carriere; Stephane Canaan; Nigam P. Rath; Christopher D. Spilling; Jean−François Cavalier

doi:10.1021/jm301216x

Synthesis and Kinetic Evaluation of Cyclophostin and Cyclipostins Phosphonate Analogs As Selective and Potent Inhibitors of Microbial Lipases

Vanessa Point
, Raj K. Malla
, Sadia Diomande
, Benjamin P. Martin
, Vincent Delorme
, Frederic Carriere
, Stephane Canaan
, Nigam P. Rath
, Christopher D. Spilling
, Jean−François Cavalier

University of Missouri-St. Louis

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Journal of Medicinal Chemistry
Volume	55
DOIs	https://doi.org/10.1021/jm301216x
State	Published - Nov 26 2012

Disciplines

Biochemistry
Organic Chemistry

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@article{d560c83933154011b2eb483c877ac2cf,

title = "Synthesis and Kinetic Evaluation of Cyclophostin and Cyclipostins Phosphonate Analogs As Selective and Potent Inhibitors of Microbial Lipases",

author = "Vanessa Point and Malla, \{Raj K.\} and Sadia Diomande and Martin, \{Benjamin P.\} and Vincent Delorme and Frederic Carriere and Stephane Canaan and Rath, \{Nigam P.\} and Spilling, \{Christopher D.\} and Jean−Fran{\c c}ois Cavalier",

note = "J Med Chem. 2012 Nov 26;55(22):10204-19. doi: 10.1021/jm301216x. Epub 2012 Nov 7. Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.",

year = "2012",

month = nov,

day = "26",

doi = "10.1021/jm301216x",

language = "American English",

volume = "55",

journal = "Journal of Medicinal Chemistry",

}

TY - JOUR

T1 - Synthesis and Kinetic Evaluation of Cyclophostin and Cyclipostins Phosphonate Analogs As Selective and Potent Inhibitors of Microbial Lipases

AU - Point, Vanessa

AU - Malla, Raj K.

AU - Diomande, Sadia

AU - Martin, Benjamin P.

AU - Delorme, Vincent

AU - Carriere, Frederic

AU - Canaan, Stephane

AU - Rath, Nigam P.

AU - Spilling, Christopher D.

AU - Cavalier, Jean−François

N1 - J Med Chem. 2012 Nov 26;55(22):10204-19. doi: 10.1021/jm301216x. Epub 2012 Nov 7. Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

PY - 2012/11/26

Y1 - 2012/11/26

UR - https://www.ncbi.nlm.nih.gov/pubmed/23095026

U2 - 10.1021/jm301216x

DO - 10.1021/jm301216x

M3 - Article

VL - 55

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

ER -

Synthesis and Kinetic Evaluation of Cyclophostin and Cyclipostins Phosphonate Analogs As Selective and Potent Inhibitors of Microbial Lipases

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