Synthesis and Kinetic Evaluation of Cyclophostin and Cyclipostins Phosphonate Analogs As Selective and Potent Inhibitors of Microbial Lipases

Vanessa Point; Raj K. Malla; Sadia Diomande; Benjamin P. Martin; Vincent Delorme; Frederic Carriere; Stephane Canaan; Nigam P. Rath; Christopher D. Spilling; Jean−François Cavalier

doi:10.1021/jm301216x

Synthesis and Kinetic Evaluation of Cyclophostin and Cyclipostins Phosphonate Analogs As Selective and Potent Inhibitors of Microbial Lipases

Vanessa Point, Raj K. Malla, Sadia Diomande, Benjamin P. Martin, Vincent Delorme, Frederic Carriere, Stephane Canaan, Nigam P. Rath, Christopher D. Spilling, Jean−François Cavalier

University of Missouri-St. Louis

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Journal of Medicinal Chemistry
Volume	55
DOIs	https://doi.org/10.1021/jm301216x
State	Published - Nov 26 2012

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Biochemistry
Organic Chemistry

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@article{d560c83933154011b2eb483c877ac2cf,

title = "Synthesis and Kinetic Evaluation of Cyclophostin and Cyclipostins Phosphonate Analogs As Selective and Potent Inhibitors of Microbial Lipases",

author = "Vanessa Point and Malla, {Raj K.} and Sadia Diomande and Martin, {Benjamin P.} and Vincent Delorme and Frederic Carriere and Stephane Canaan and Rath, {Nigam P.} and Spilling, {Christopher D.} and Jean−Fran{\c c}ois Cavalier",

note = "J Med Chem. 2012 Nov 26;55(22):10204-19. doi: 10.1021/jm301216x. Epub 2012 Nov 7. Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.",

year = "2012",

month = nov,

day = "26",

doi = "10.1021/jm301216x",

language = "American English",

volume = "55",

journal = "Journal of Medicinal Chemistry",

}

TY - JOUR

T1 - Synthesis and Kinetic Evaluation of Cyclophostin and Cyclipostins Phosphonate Analogs As Selective and Potent Inhibitors of Microbial Lipases

AU - Point, Vanessa

AU - Malla, Raj K.

AU - Diomande, Sadia

AU - Martin, Benjamin P.

AU - Delorme, Vincent

AU - Carriere, Frederic

AU - Canaan, Stephane

AU - Rath, Nigam P.

AU - Spilling, Christopher D.

AU - Cavalier, Jean−François

N1 - J Med Chem. 2012 Nov 26;55(22):10204-19. doi: 10.1021/jm301216x. Epub 2012 Nov 7. Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

PY - 2012/11/26

Y1 - 2012/11/26

UR - https://www.ncbi.nlm.nih.gov/pubmed/23095026

U2 - 10.1021/jm301216x

DO - 10.1021/jm301216x

M3 - Article

VL - 55

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

ER -

Synthesis and Kinetic Evaluation of Cyclophostin and Cyclipostins Phosphonate Analogs As Selective and Potent Inhibitors of Microbial Lipases

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