Synthesis and Kinetic Analysis of Some Phosphonate Analogs of Cyclophostin as Inhibitors of Human Acetylcholinesterase

Supratik Dutta; Raj K. Malla; Saibal Bandyopadhyay; Christopher D. Spilling; Cynthia M. Dupureur

doi:10.1016/j.bmc.2010.01.063

Synthesis and Kinetic Analysis of Some Phosphonate Analogs of Cyclophostin as Inhibitors of Human Acetylcholinesterase

Supratik Dutta
, Raj K. Malla
, Saibal Bandyopadhyay
, Christopher D. Spilling
, Cynthia M. Dupureur

University of Missouri-St. Louis

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Bioorganic & Medicinal Chemistry
Volume	18
DOIs	https://doi.org/10.1016/j.bmc.2010.01.063
State	Published - Mar 1 2010

Disciplines

Biochemistry
Organic Chemistry

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@article{aff5ddb672614ac49265ab1c41cec17d,

title = "Synthesis and Kinetic Analysis of Some Phosphonate Analogs of Cyclophostin as Inhibitors of Human Acetylcholinesterase",

author = "Supratik Dutta and Malla, \{Raj K.\} and Saibal Bandyopadhyay and Spilling, \{Christopher D.\} and Dupureur, \{Cynthia M.\}",

note = "Two new monocyclic analogs of the natural AChE inhibitor cyclophostin and two exocyclic enol phosphates were synthesized. The potencies and mechanisms...",

year = "2010",

month = mar,

day = "1",

doi = "10.1016/j.bmc.2010.01.063",

language = "American English",

volume = "18",

journal = "Bioorganic \& Medicinal Chemistry",

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TY - JOUR

T1 - Synthesis and Kinetic Analysis of Some Phosphonate Analogs of Cyclophostin as Inhibitors of Human Acetylcholinesterase

AU - Dutta, Supratik

AU - Malla, Raj K.

AU - Bandyopadhyay, Saibal

AU - Spilling, Christopher D.

AU - Dupureur, Cynthia M.

N1 - Two new monocyclic analogs of the natural AChE inhibitor cyclophostin and two exocyclic enol phosphates were synthesized. The potencies and mechanisms...

PY - 2010/3/1

Y1 - 2010/3/1

UR - https://www.sciencedirect.com/science/article/pii/S0968089610000945

U2 - 10.1016/j.bmc.2010.01.063

DO - 10.1016/j.bmc.2010.01.063

M3 - Article

VL - 18

JO - Bioorganic & Medicinal Chemistry

JF - Bioorganic & Medicinal Chemistry

ER -

Synthesis and Kinetic Analysis of Some Phosphonate Analogs of Cyclophostin as Inhibitors of Human Acetylcholinesterase

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