Synthesis and Kinetic Analysis of Some Phosphonate Analogs of Cyclophostin as Inhibitors of Human Acetylcholinesterase

Supratik Dutta; Raj K. Malla; Saibal Bandyopadhyay; Christopher D. Spilling; Cynthia M. Dupureur

doi:10.1016/j.bmc.2010.01.063

Synthesis and Kinetic Analysis of Some Phosphonate Analogs of Cyclophostin as Inhibitors of Human Acetylcholinesterase

Supratik Dutta, Raj K. Malla, Saibal Bandyopadhyay, Christopher D. Spilling, Cynthia M. Dupureur

University of Missouri-St. Louis

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Bioorganic & Medicinal Chemistry
Volume	18
DOIs	https://doi.org/10.1016/j.bmc.2010.01.063
State	Published - Mar 1 2010

Disciplines

Biochemistry
Organic Chemistry

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title = "Synthesis and Kinetic Analysis of Some Phosphonate Analogs of Cyclophostin as Inhibitors of Human Acetylcholinesterase",

author = "Supratik Dutta and Malla, {Raj K.} and Saibal Bandyopadhyay and Spilling, {Christopher D.} and Dupureur, {Cynthia M.}",

note = "Two new monocyclic analogs of the natural AChE inhibitor cyclophostin and two exocyclic enol phosphates were synthesized. The potencies and mechanisms...",

year = "2010",

month = mar,

day = "1",

doi = "10.1016/j.bmc.2010.01.063",

language = "American English",

volume = "18",

journal = "Bioorganic & Medicinal Chemistry",

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TY - JOUR

T1 - Synthesis and Kinetic Analysis of Some Phosphonate Analogs of Cyclophostin as Inhibitors of Human Acetylcholinesterase

AU - Dutta, Supratik

AU - Malla, Raj K.

AU - Bandyopadhyay, Saibal

AU - Spilling, Christopher D.

AU - Dupureur, Cynthia M.

N1 - Two new monocyclic analogs of the natural AChE inhibitor cyclophostin and two exocyclic enol phosphates were synthesized. The potencies and mechanisms...

PY - 2010/3/1

Y1 - 2010/3/1

UR - https://www.sciencedirect.com/science/article/pii/S0968089610000945

U2 - 10.1016/j.bmc.2010.01.063

DO - 10.1016/j.bmc.2010.01.063

M3 - Article

VL - 18

JO - Bioorganic & Medicinal Chemistry

JF - Bioorganic & Medicinal Chemistry

ER -

Synthesis and Kinetic Analysis of Some Phosphonate Analogs of Cyclophostin as Inhibitors of Human Acetylcholinesterase

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