Structure–Activity Studies of Non-Steroid Analogues Structurally-Related to Neuroprotective Estrogens

Mingxing Qian; Elizabeth B. Engler-Chiurazzi; Sara E. Lewis; Nigam P. Rath; James W. Simpkins; Douglas F. Covey

doi:10.1039/C6OB01726F

Structure–Activity Studies of Non-Steroid Analogues Structurally-Related to Neuroprotective Estrogens

Mingxing Qian
, Elizabeth B. Engler-Chiurazzi
, Sara E. Lewis
, Nigam P. Rath
, James W. Simpkins
, Douglas F. Covey

University of Missouri-St. Louis

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Organic and Biomolecular Chemistry
Volume	14
DOIs	https://doi.org/10.1039/C6OB01726F
State	Published - Jan 1 2016

Disciplines

Biochemistry
Organic Chemistry

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10.1039/C6OB01726FLicense: Unspecified

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@article{35f244099d4142b9bb4b406f6637bda6,

title = "Structure–Activity Studies of Non-Steroid Analogues Structurally-Related to Neuroprotective Estrogens",

author = "Mingxing Qian and Engler-Chiurazzi, \{Elizabeth B.\} and Lewis, \{Sara E.\} and Rath, \{Nigam P.\} and Simpkins, \{James W.\} and Covey, \{Douglas F.\}",

note = "Estrone and 17β-estradiol are phenolic steroids that are known to be neuroprotective in multiple models of neuronal injury. Previous studies have identified the importance of their phenolic steroid A-ring for neuroprotection and have identified ortho substituents at the C-2 and C-4 positions on the phenol ri",

year = "2016",

month = jan,

day = "1",

doi = "10.1039/C6OB01726F",

language = "American English",

volume = "14",

journal = "Organic and Biomolecular Chemistry",

}

TY - JOUR

T1 - Structure–Activity Studies of Non-Steroid Analogues Structurally-Related to Neuroprotective Estrogens

AU - Qian, Mingxing

AU - Engler-Chiurazzi, Elizabeth B.

AU - Lewis, Sara E.

AU - Rath, Nigam P.

AU - Simpkins, James W.

AU - Covey, Douglas F.

N1 - Estrone and 17β-estradiol are phenolic steroids that are known to be neuroprotective in multiple models of neuronal injury. Previous studies have identified the importance of their phenolic steroid A-ring for neuroprotection and have identified ortho substituents at the C-2 and C-4 positions on the phenol ri

PY - 2016/1/1

Y1 - 2016/1/1

UR - https://pubs.rsc.org/en/content/articlelanding/2016/ob/c6ob01726f?_escaped_fragment_=

U2 - 10.1039/C6OB01726F

DO - 10.1039/C6OB01726F

M3 - Article

VL - 14

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

ER -

Structure–Activity Studies of Non-Steroid Analogues Structurally-Related to Neuroprotective Estrogens

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