Structure of a novel antimalarial gallium(III) complex with selective activity against chloroquine-resistant Plasmodium falciparum

Vijay Sharma; Alicia Beatty; Daniel E. Goldberg; David Piwnica-Worms

doi:10.1039/a705563c

Structure of a novel antimalarial gallium(III) complex with selective activity against chloroquine-resistant Plasmodium falciparum

Vijay Sharma
, Alicia Beatty
, Daniel E. Goldberg
, David Piwnica-Worms

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Chemical Communications
Volume	29
DOIs	https://doi.org/10.1039/a705563c
State	Published - Jan 1 1997
Externally published	Yes

Disciplines

Biochemistry
Organic Chemistry
Inorganic Chemistry

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@article{6daabb0897584afeaf2e8c0a7536d996,

title = "Structure of a novel antimalarial gallium(III) complex with selective activity against chloroquine-resistant Plasmodium falciparum",

author = "Vijay Sharma and Alicia Beatty and Goldberg, \{Daniel E.\} and David Piwnica-Worms",

note = "The crystal structure of an amine phenol complex of gallium(III), [\{1,12-bis(2-hydroxy-3-methoxybenzyl)-1,5,8,12-tetraazadodecane\}gallium(III)] [Ga(madd)]+, a potent new antimalarial which selectively targets chloroquine-resistant organisms is reported; the compound is shown to directly inhibit heme polymerization.",

year = "1997",

month = jan,

day = "1",

doi = "10.1039/a705563c",

language = "American English",

volume = "29",

journal = "Chemical Communications",

}

TY - JOUR

T1 - Structure of a novel antimalarial gallium(III) complex with selective activity against chloroquine-resistant Plasmodium falciparum

AU - Sharma, Vijay

AU - Beatty, Alicia

AU - Goldberg, Daniel E.

AU - Piwnica-Worms, David

N1 - The crystal structure of an amine phenol complex of gallium(III), [{1,12-bis(2-hydroxy-3-methoxybenzyl)-1,5,8,12-tetraazadodecane}gallium(III)] [Ga(madd)]+, a potent new antimalarial which selectively targets chloroquine-resistant organisms is reported; the compound is shown to directly inhibit heme polymerization.

PY - 1997/1/1

Y1 - 1997/1/1

UR - https://mdanderson.elsevierpure.com/en/publications/structure-of-a-novel-antimalarial-galliumiii-complex-with-selecti

U2 - 10.1039/a705563c

DO - 10.1039/a705563c

M3 - Article

VL - 29

JO - Chemical Communications

JF - Chemical Communications

ER -

Structure of a novel antimalarial gallium(III) complex with selective activity against chloroquine-resistant Plasmodium falciparum

Disciplines

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