TY - CHAP
T1 - Selective Modifications of Cyclodextrins
AU - Khan, Abdul Rauf
AU - Forgo, Peter
AU - Stine, Keith J.
AU - D’Souza, Valerian T.
N1 - It is indeed a pleasure and an honor to present this talk at the beautiful and ancient city of Santiago de Compostela and I would like to thank the organizers for giving me an opportunity to do so....
PY - 1999/1/1
Y1 - 1999/1/1
N2 - It is indeed a pleasure and an honor to present this talk at the beautiful and ancient city of Santiago de Compostela and I would like to thank the organizers for giving me an opportunity to do so. We all love cyclodextrins and we like to study them, use them, play with them and even make some money out of them. The question is, if they are so incredible molecules, why do we need to change them? The answer is that in spite of their extraordinary properties, limitations of available functional groups and rigidity of their structure restrict our ability to utilize them. A number of very prominent chemists have attempted to rectify this situation and have provided us with methods to modify them.1 In this talk, I will present our contribution to this effort. I will first introduce the chemistry involved in selective modification of cyclodextrin, then I will discuss mono-modification of cyclodextrins in which we have attached the same group (4-methylamino-3-nitro-benzyl group) selectively at the 2-, 3- and the 6-positions. I will then present our contribution in per-modification of cyclodextrins.
AB - It is indeed a pleasure and an honor to present this talk at the beautiful and ancient city of Santiago de Compostela and I would like to thank the organizers for giving me an opportunity to do so. We all love cyclodextrins and we like to study them, use them, play with them and even make some money out of them. The question is, if they are so incredible molecules, why do we need to change them? The answer is that in spite of their extraordinary properties, limitations of available functional groups and rigidity of their structure restrict our ability to utilize them. A number of very prominent chemists have attempted to rectify this situation and have provided us with methods to modify them.1 In this talk, I will present our contribution to this effort. I will first introduce the chemistry involved in selective modification of cyclodextrin, then I will discuss mono-modification of cyclodextrins in which we have attached the same group (4-methylamino-3-nitro-benzyl group) selectively at the 2-, 3- and the 6-positions. I will then present our contribution in per-modification of cyclodextrins.
UR - https://rd.springer.com/content/pdf/10.1007%2F978-94-011-4681-4_8.pdf
U2 - 10.1007/978-94-011-4681-4_8
DO - 10.1007/978-94-011-4681-4_8
M3 - Chapter
BT - Proceedings of the Ninth International Symposium on Cyclodextrins
ER -