Saccharide conjugates

Alexei V. Demchenko; Michael Nichols; Sophon Kaeothip

Saccharide conjugates

Alexei V. Demchenko, Michael Nichols, Sophon Kaeothip

University of Missouri-St. Louis

Research output: Other contribution

Abstract

The invention provides a series of novel Lipid A analogs that are structurally simple, synthetically accessible, and capable of blocking the cellular receptor within the signal transduction pathway. The novel Lipid A analogs can include a monosaccharide core with hydrophobic side chains and amino acid ionic motif. The invention further provides methods of using the compounds and compositions thereof in various therapeutic methods.

Original language	American English
State	Published - Sep 1 2015

Disciplines

Biochemistry, Biophysics, and Structural Biology
Chemistry

Cite this

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title = "Saccharide conjugates",

abstract = " The invention provides a series of novel Lipid A analogs that are structurally simple, synthetically accessible, and capable of blocking the cellular receptor within the signal transduction pathway. The novel Lipid A analogs can include a monosaccharide core with hydrophobic side chains and amino acid ionic motif. The invention further provides methods of using the compounds and compositions thereof in various therapeutic methods. ",

author = "Demchenko, {Alexei V.} and Michael Nichols and Sophon Kaeothip",

year = "2015",

month = sep,

day = "1",

language = "American English",

type = "Other",

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TY - GEN

T1 - Saccharide conjugates

AU - Demchenko, Alexei V.

AU - Nichols, Michael

AU - Kaeothip, Sophon

PY - 2015/9/1

Y1 - 2015/9/1

N2 - The invention provides a series of novel Lipid A analogs that are structurally simple, synthetically accessible, and capable of blocking the cellular receptor within the signal transduction pathway. The novel Lipid A analogs can include a monosaccharide core with hydrophobic side chains and amino acid ionic motif. The invention further provides methods of using the compounds and compositions thereof in various therapeutic methods.

AB - The invention provides a series of novel Lipid A analogs that are structurally simple, synthetically accessible, and capable of blocking the cellular receptor within the signal transduction pathway. The novel Lipid A analogs can include a monosaccharide core with hydrophobic side chains and amino acid ionic motif. The invention further provides methods of using the compounds and compositions thereof in various therapeutic methods.

UR - https://irl.umsl.edu/cgi/viewcontent.cgi?article=1033context=patents

M3 - Other contribution

ER -

Saccharide conjugates

Abstract

Disciplines

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Cite this