Reverse Orthogonal Strategy for Oligosaccharide Synthesis

Kohki Fujikawa, N. Vijaya Ganesh, Yih Horng Tan, Keith J. Stine, Alexei V. Demchenko

Research output: Contribution to journalArticlepeer-review

Abstract

Herein, we report the invention of a novel expeditious concept for oligosaccharide synthesis. Unlike the classic orthogonal strategy based on leaving groups, the reverse approach is based on orthogonal protecting groups, herein p-methoxybenzyl and 4-pentenoyl, which allows for efficient oligosaccharide assembly in the reverse direction.

Original languageAmerican English
JournalChemical Communications
Volume47
DOIs
StatePublished - Jan 1 2011

Disciplines

  • Organic Chemistry
  • Biochemistry

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