Recent Advances in Stereocontrolled Mannosylation: Focus on Glycans Comprising Acidic and/or Amino Sugars

Catherine Alex; Alexei Demchenko

doi:10.1002/TCR.202100201

Recent Advances in Stereocontrolled Mannosylation: Focus on Glycans Comprising Acidic and/or Amino Sugars

Catherine Alex, Alexei Demchenko

University of Missouri-St. Louis

Research output: Contribution to journal › Article › peer-review

Abstract

The main focus of this review is to describe accomplishments made in the stereoselective synthesis of β -linked mannosides functionalized with carboxyls or amines/amides. These ManNAc, ManA and ManNAcA residues found in many glycoconjugates, bacterial polysaccharides, and alginates have consistently captured interest of the glycoscience community both due to synthetic challenge and therapeutic potential.

Original language	American English
Journal	Chemical Record
Volume	21
DOIs	https://doi.org/10.1002/TCR.202100201
State	Published - Nov 2021

Disciplines

Biochemistry, Biophysics, and Structural Biology

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10.1002/TCR.202100201License: Unspecified

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title = "Recent Advances in Stereocontrolled Mannosylation: Focus on Glycans Comprising Acidic and/or Amino Sugars",

abstract = " The main focus of this review is to describe accomplishments made in the stereoselective synthesis of β -linked mannosides functionalized with carboxyls or amines/amides. These ManNAc, ManA and ManNAcA residues found in many glycoconjugates, bacterial polysaccharides, and alginates have consistently captured interest of the glycoscience community both due to synthetic challenge and therapeutic potential. ",

author = "Catherine Alex and Alexei Demchenko",

year = "2021",

month = nov,

doi = "10.1002/TCR.202100201",

language = "American English",

volume = "21",

journal = "Chemical Record",

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AU - Alex, Catherine

AU - Demchenko, Alexei

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N2 - The main focus of this review is to describe accomplishments made in the stereoselective synthesis of β -linked mannosides functionalized with carboxyls or amines/amides. These ManNAc, ManA and ManNAcA residues found in many glycoconjugates, bacterial polysaccharides, and alginates have consistently captured interest of the glycoscience community both due to synthetic challenge and therapeutic potential.

AB - The main focus of this review is to describe accomplishments made in the stereoselective synthesis of β -linked mannosides functionalized with carboxyls or amines/amides. These ManNAc, ManA and ManNAcA residues found in many glycoconjugates, bacterial polysaccharides, and alginates have consistently captured interest of the glycoscience community both due to synthetic challenge and therapeutic potential.

UR - https://doi.org/10.1002/TCR.202100201

U2 - 10.1002/TCR.202100201

DO - 10.1002/TCR.202100201

M3 - Article

VL - 21

JO - Chemical Record

JF - Chemical Record

ER -

Recent Advances in Stereocontrolled Mannosylation: Focus on Glycans Comprising Acidic and/or Amino Sugars

Abstract

Disciplines

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