Neurosteroid analogues. 9. Conformationally constrained pregnanes: Structure-activity studies of 13,24-cyclo-18,21-dinorcholane analogues of the GABA modulatory and anesthetic steroids (3α, 5α)- and (3α, 5β)-3-hydroxypregnan-20-one

title = "Neurosteroid analogues. 9. Conformationally constrained pregnanes: Structure-activity studies of 13,24-cyclo-18,21-dinorcholane analogues of the GABA modulatory and anesthetic steroids (3α, 5α)- and (3α, 5β)-3-hydroxypregnan-20-one",

author = "Xin Jiang and Manion, \{Brad D.\} and Ann Benz and Rath, \{Nigam P.\} and Evers, \{Alex S.\} and Zorumski, \{Charles F.\} and Steven Mennerick and Covey, \{Douglas F.\}",

note = "J Med Chem. 2003 Dec 4;46(25):5334-48. Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.",

year = "2003",

month = dec,

day = "1",

doi = "10.1021/jm030302m",

language = "American English",

volume = "46",

journal = "Journal of Medicinal Chemistry",

}

TY - JOUR

T1 - Neurosteroid analogues. 9. Conformationally constrained pregnanes: Structure-activity studies of 13,24-cyclo-18,21-dinorcholane analogues of the GABA modulatory and anesthetic steroids (3α, 5α)- and (3α, 5β)-3-hydroxypregnan-20-one

AU - Jiang, Xin

AU - Manion, Brad D.

AU - Benz, Ann

AU - Rath, Nigam P.

AU - Evers, Alex S.

AU - Zorumski, Charles F.

AU - Mennerick, Steven

AU - Covey, Douglas F.

N1 - J Med Chem. 2003 Dec 4;46(25):5334-48. Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

PY - 2003/12/1

Y1 - 2003/12/1

UR - https://www.ncbi.nlm.nih.gov/pubmed/14640542

U2 - 10.1021/jm030302m

DO - 10.1021/jm030302m

M3 - Article

VL - 46

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

ER -

Neurosteroid analogues. 9. Conformationally constrained pregnanes: Structure-activity studies of 13,24-cyclo-18,21-dinorcholane analogues of the GABA modulatory and anesthetic steroids (3α, 5α)- and (3α, 5β)-3-hydroxypregnan-20-one

Disciplines

Access to Document

Other files and links

Cite this