Neurosteroid Analogues. 15. A Comparative Study of the Anesthetic and Gabaergic Actions of Alphaxalone, δ16-Alphaxalone and Their Corresponding 17-Carbonitrile Analogues

Achintya K. Bandyopadhyaya; Brad D. Manion; Ann Benz; Amanda Taylor; Nigam P. Rath; Alex S. Evers; Charles F. Zorumski; Steven Mennerick; Douglas F. Covey

doi:10.1016/j.bmcl.2010.09.008

Neurosteroid Analogues. 15. A Comparative Study of the Anesthetic and Gabaergic Actions of Alphaxalone, δ16-Alphaxalone and Their Corresponding 17-Carbonitrile Analogues

Achintya K. Bandyopadhyaya, Brad D. Manion, Ann Benz, Amanda Taylor, Nigam P. Rath, Alex S. Evers, Charles F. Zorumski, Steven Mennerick, Douglas F. Covey

University of Missouri-St. Louis

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Bioorganic & Medicinal Chemistry Letters
Volume	20
DOIs	https://doi.org/10.1016/j.bmcl.2010.09.008
State	Published - Nov 1 2010

Disciplines

Biochemistry
Chemistry

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Bandyopadhyaya, A. K., Manion, B. D., Benz, A., Taylor, A., Rath, N. P., Evers, A. S., Zorumski, C. F., Mennerick, S., & Covey, D. F. (2010). Neurosteroid Analogues. 15. A Comparative Study of the Anesthetic and Gabaergic Actions of Alphaxalone, δ16-Alphaxalone and Their Corresponding 17-Carbonitrile Analogues. Bioorganic & Medicinal Chemistry Letters, 20. https://doi.org/10.1016/j.bmcl.2010.09.008

Neurosteroid Analogues. 15. A Comparative Study of the Anesthetic and Gabaergic Actions of Alphaxalone, δ16-Alphaxalone and Their Corresponding 17-Carbonitrile Analogues. / Bandyopadhyaya, Achintya K.; Manion, Brad D.; Benz, Ann et al.
In: Bioorganic & Medicinal Chemistry Letters, Vol. 20, 01.11.2010.

Research output: Contribution to journal › Article › peer-review

Bandyopadhyaya, AK, Manion, BD, Benz, A, Taylor, A , Rath, NP, Evers, AS, Zorumski, CF, Mennerick, S & Covey, DF 2010, 'Neurosteroid Analogues. 15. A Comparative Study of the Anesthetic and Gabaergic Actions of Alphaxalone, δ16-Alphaxalone and Their Corresponding 17-Carbonitrile Analogues', Bioorganic & Medicinal Chemistry Letters, vol. 20. https://doi.org/10.1016/j.bmcl.2010.09.008

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author = "Bandyopadhyaya, {Achintya K.} and Manion, {Brad D.} and Ann Benz and Amanda Taylor and Rath, {Nigam P.} and Evers, {Alex S.} and Zorumski, {Charles F.} and Steven Mennerick and Covey, {Douglas F.}",

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AU - Bandyopadhyaya, Achintya K.

AU - Manion, Brad D.

AU - Benz, Ann

AU - Taylor, Amanda

AU - Rath, Nigam P.

AU - Evers, Alex S.

AU - Zorumski, Charles F.

AU - Mennerick, Steven

AU - Covey, Douglas F.

N1 - Alphaxalone, a neuroactive steroid containing a 17β-acetyl group, has potent anesthetic activity in humans. This pharmacological activity is attribute...

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M3 - Article

VL - 20

JO - Bioorganic & Medicinal Chemistry Letters

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ER -

Neurosteroid Analogues. 15. A Comparative Study of the Anesthetic and Gabaergic Actions of Alphaxalone, δ16-Alphaxalone and Their Corresponding 17-Carbonitrile Analogues

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