Modulating DNA by polyamides to regulate transcription factor PU.1-DNA binding interactions

Beibei Liu; James K. Bashkin; Gregory M.K. Poon; Shuo Wang; Siming Wang; W. David Wilson

doi:10.1016/j.biochi.2019.08.009

Modulating DNA by polyamides to regulate transcription factor PU.1-DNA binding interactions

Beibei Liu, James K. Bashkin, Gregory M.K. Poon, Shuo Wang, Siming Wang, W. David Wilson

University of Missouri-St. Louis

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Biochimie
Volume	167
DOIs	https://doi.org/10.1016/j.biochi.2019.08.009
State	Published - Dec 1 2019

Disciplines

Biology
Cell Biology
Biochemistry

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@article{83df2452126f4092b6d85a955eba951a,

title = "Modulating DNA by polyamides to regulate transcription factor PU.1-DNA binding interactions",

author = "Beibei Liu and Bashkin, {James K.} and Poon, {Gregory M.K.} and Shuo Wang and Siming Wang and Wilson, {W. David}",

note = "JavaScript is disabled on your browser. Please enable JavaScript to use all the features on this page. * New hairpin polyamides were synthesized. * The polyamides recognized the PU.1 promoter DNA sequence. * The polyamides were able to inhibit PU.1 binding to the promoter. * Inhibition correlated with the polyamide binding affinity.",

year = "2019",

month = dec,

day = "1",

doi = "10.1016/j.biochi.2019.08.009",

language = "American English",

volume = "167",

journal = "Biochimie",

}

TY - JOUR

T1 - Modulating DNA by polyamides to regulate transcription factor PU.1-DNA binding interactions

AU - Liu, Beibei

AU - Bashkin, James K.

AU - Poon, Gregory M.K.

AU - Wang, Shuo

AU - Wang, Siming

AU - Wilson, W. David

N1 - JavaScript is disabled on your browser. Please enable JavaScript to use all the features on this page. * New hairpin polyamides were synthesized. * The polyamides recognized the PU.1 promoter DNA sequence. * The polyamides were able to inhibit PU.1 binding to the promoter. * Inhibition correlated with the polyamide binding affinity.

PY - 2019/12/1

Y1 - 2019/12/1

UR - https://www.sciencedirect.com/science/article/pii/S030090841930241X

U2 - 10.1016/j.biochi.2019.08.009

DO - 10.1016/j.biochi.2019.08.009

M3 - Article

VL - 167

JO - Biochimie

JF - Biochimie

ER -

Modulating DNA by polyamides to regulate transcription factor PU.1-DNA binding interactions

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