High affinity glycosaminoglycan and autoantigen interaction explains joint specificity in a mouse model of rheumatoid arthritis

Daniel R. Studelska; Laura Mandik-Nayak; Xiaodong Zhou; Jing Pan; Peter Weiser; Lynda M. McDowell; Hong Lu; Helen Liapis; Paul M. Allen; Fei F. Shih; Lijuan Zhang

doi:10.1074/jbc.M806458200

High affinity glycosaminoglycan and autoantigen interaction explains joint specificity in a mouse model of rheumatoid arthritis

Daniel R. Studelska, Laura Mandik-Nayak, Xiaodong Zhou, Jing Pan, Peter Weiser, Lynda M. McDowell, Hong Lu, Helen Liapis, Paul M. Allen, Fei F. Shih, Lijuan Zhang

University of Missouri-St. Louis

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Journal of Biological Chemistry
Volume	284
DOIs	https://doi.org/10.1074/jbc.M806458200
State	Published - Jan 23 2009

Disciplines

Biochemistry
Biology
Molecular Biology

Access to Document

10.1074/jbc.M806458200License: Unspecified

Cite this

@article{5a2a557e46444dc0b6ce575284123633,

title = "High affinity glycosaminoglycan and autoantigen interaction explains joint specificity in a mouse model of rheumatoid arthritis",

author = "Studelska, \{Daniel R.\} and Laura Mandik-Nayak and Xiaodong Zhou and Jing Pan and Peter Weiser and McDowell, \{Lynda M.\} and Hong Lu and Helen Liapis and Allen, \{Paul M.\} and Shih, \{Fei F.\} and Lijuan Zhang",

note = "In the K/BxN mouse model of rheumatoid arthritis, autoantibodies specific for glucose-6-phosphate isomerase (GPI) can transfer joint-specific inflammation to most strains of normal mice. Binding of GPI and autoantibody to the joint surface is a prerequisite for joint-specific inflammation. However, how GPI localizes to the joint remains unclear.",

year = "2009",

month = jan,

day = "23",

doi = "10.1074/jbc.M806458200",

language = "American English",

volume = "284",

journal = "Journal of Biological Chemistry",

}

TY - JOUR

T1 - High affinity glycosaminoglycan and autoantigen interaction explains joint specificity in a mouse model of rheumatoid arthritis

AU - Studelska, Daniel R.

AU - Mandik-Nayak, Laura

AU - Zhou, Xiaodong

AU - Pan, Jing

AU - Weiser, Peter

AU - McDowell, Lynda M.

AU - Lu, Hong

AU - Liapis, Helen

AU - Allen, Paul M.

AU - Shih, Fei F.

AU - Zhang, Lijuan

N1 - In the K/BxN mouse model of rheumatoid arthritis, autoantibodies specific for glucose-6-phosphate isomerase (GPI) can transfer joint-specific inflammation to most strains of normal mice. Binding of GPI and autoantibody to the joint surface is a prerequisite for joint-specific inflammation. However, how GPI localizes to the joint remains unclear.

PY - 2009/1/23

Y1 - 2009/1/23

UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629098/

U2 - 10.1074/jbc.M806458200

DO - 10.1074/jbc.M806458200

M3 - Article

VL - 284

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

ER -

High affinity glycosaminoglycan and autoantigen interaction explains joint specificity in a mouse model of rheumatoid arthritis

Disciplines

Access to Document

Other files and links

Cite this