Glycans in Mesoporous and Nanoporous Materials

Keith J. Stine

doi:10.1002/9781118860212.ch9

Glycans in Mesoporous and Nanoporous Materials

Keith J. Stine

University of Missouri-St. Louis

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

<div class="line" id="line-27"> Porous or “nanoporous” materials have thus far found applications in glycan enrichment, separation, detection, drug delivery, and supported synthesis. This chapter presents a survey of applications of porous materials in glycoscience, including mesoporous silica, mesoporous carbon, porous alumina, porous titania, porous polymer monoliths, and nanoporous gold. Nanoporous materials also clearly have great promise to continue to find new applications in assays and biosensors for glycopro&hyphen;teins. Nanoporous materials that can be conveniently surface modified with complex molecular architectures such as mixed self&hyphen;assembled monolayers (SAMs), bound glycopolymers, and reactive functional groups are especially of interest. The integration of such modified nano&hyphen;materials with analytical systems in chromatography and mass spectroscopy is also primed for further advancement, as are applications in the separation, purification, and production systems for glycoproteins and other glycoconjugates.</div><div class="line" id="line-29"> <br/></div>

Original language	American English
Title of host publication	Carbohydrate Nanotechnology
DOIs	https://doi.org/10.1002/9781118860212.ch9
State	Published - Nov 27 2015

Disciplines

Organic Chemistry
Materials Science and Engineering

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abstract = " Porous or “nanoporous” materials have thus far found applications in glycan enrichment, separation, detection, drug delivery, and supported synthesis. This chapter presents a survey of applications of porous materials in glycoscience, including mesoporous silica, mesoporous carbon, porous alumina, porous titania, porous polymer monoliths, and nanoporous gold. Nanoporous materials also clearly have great promise to continue to find new applications in assays and biosensors for glycopro&hyphen;teins. Nanoporous materials that can be conveniently surface modified with complex molecular architectures such as mixed self&hyphen;assembled monolayers (SAMs), bound glycopolymers, and reactive functional groups are especially of interest. The integration of such modified nano&hyphen;materials with analytical systems in chromatography and mass spectroscopy is also primed for further advancement, as are applications in the separation, purification, and production systems for glycoproteins and other glycoconjugates. ",

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M3 - Chapter

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ER -

Glycans in Mesoporous and Nanoporous Materials

Abstract

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