Enantiospecificity of Sterol–lipid Interactions: First Evidence that the Absolute Configuration of Cholesterol Affects the Physical Properties of Cholesterol–Sphingomyelin Membranes

S. Lalitha, A. Sampath Kumar, Keith J. Stine, Douglas F. Covey

Research output: Contribution to journalArticlepeer-review

Abstract

Results from monolayer studies using the enantiomers of cholesterol (nat- and ent-cholesterol) and egg yolk sphingomyelin show for the first time that enantiospecific interactions between sterols and lipids can affect the physical properties of membranes.

Original languageAmerican English
JournalChemical Communications
Volume32
DOIs
StatePublished - Jan 1 2001

Disciplines

  • Biochemistry
  • Organic Chemistry

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