Discovery of chiral N, N-disubstituted trifluoro-3-amino-2-propanols as potent inhibitors of cholesteryl ester transfer protein

Richard C. Durley; Margaret L. Grapperhaus; Mark A. Massa; Deborah A. Mischke; Barry L. Parnas; Yvette M. Fobian; Nigam P. Rath; Dorothy D. Honda; Ming Zeng; Daniel T. Connolly; Deborah M. Heuvelman; Bryan J. Witherbee; Kevin C. Glenn; Elaine S. Krul; Mark E. Smith; James A. Sikorski

doi:10.1021/jm000337b

Discovery of chiral N, N-disubstituted trifluoro-3-amino-2-propanols as potent inhibitors of cholesteryl ester transfer protein

Richard C. Durley, Margaret L. Grapperhaus, Mark A. Massa, Deborah A. Mischke, Barry L. Parnas, Yvette M. Fobian, Nigam P. Rath, Dorothy D. Honda, Ming Zeng, Daniel T. Connolly, Deborah M. Heuvelman, Bryan J. Witherbee, Kevin C. Glenn, Elaine S. Krul, Mark E. Smith, James A. Sikorski

University of Missouri-St. Louis

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Journal of Medicinal Chemistry
Volume	43
DOIs	https://doi.org/10.1021/jm000337b
State	Published - Nov 1 2000

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Biochemistry
Organic Chemistry

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Durley, R. C., Grapperhaus, M. L., Massa, M. A., Mischke, D. A., Parnas, B. L., Fobian, Y. M., Rath, N. P., Honda, D. D., Zeng, M., Connolly, D. T., Heuvelman, D. M., Witherbee, B. J., Glenn, K. C., Krul, E. S., Smith, M. E., & Sikorski, J. A. (2000). Discovery of chiral N, N-disubstituted trifluoro-3-amino-2-propanols as potent inhibitors of cholesteryl ester transfer protein. Journal of Medicinal Chemistry, 43. https://doi.org/10.1021/jm000337b

Durley, RC, Grapperhaus, ML, Massa, MA, Mischke, DA, Parnas, BL, Fobian, YM, Rath, NP, Honda, DD, Zeng, M, Connolly, DT, Heuvelman, DM, Witherbee, BJ, Glenn, KC, Krul, ES, Smith, ME & Sikorski, JA 2000, 'Discovery of chiral N, N-disubstituted trifluoro-3-amino-2-propanols as potent inhibitors of cholesteryl ester transfer protein', Journal of Medicinal Chemistry, vol. 43. https://doi.org/10.1021/jm000337b

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title = "Discovery of chiral N, N-disubstituted trifluoro-3-amino-2-propanols as potent inhibitors of cholesteryl ester transfer protein",

author = "Durley, \{Richard C.\} and Grapperhaus, \{Margaret L.\} and Massa, \{Mark A.\} and Mischke, \{Deborah A.\} and Parnas, \{Barry L.\} and Fobian, \{Yvette M.\} and Rath, \{Nigam P.\} and Honda, \{Dorothy D.\} and Ming Zeng and Connolly, \{Daniel T.\} and Heuvelman, \{Deborah M.\} and Witherbee, \{Bryan J.\} and Glenn, \{Kevin C.\} and Krul, \{Elaine S.\} and Smith, \{Mark E.\} and Sikorski, \{James A.\}",

year = "2000",

month = nov,

day = "1",

doi = "10.1021/jm000337b",

language = "American English",

volume = "43",

journal = "Journal of Medicinal Chemistry",

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TY - JOUR

T1 - Discovery of chiral N, N-disubstituted trifluoro-3-amino-2-propanols as potent inhibitors of cholesteryl ester transfer protein

AU - Durley, Richard C.

AU - Grapperhaus, Margaret L.

AU - Massa, Mark A.

AU - Mischke, Deborah A.

AU - Parnas, Barry L.

AU - Fobian, Yvette M.

AU - Rath, Nigam P.

AU - Honda, Dorothy D.

AU - Zeng, Ming

AU - Connolly, Daniel T.

AU - Heuvelman, Deborah M.

AU - Witherbee, Bryan J.

AU - Glenn, Kevin C.

AU - Krul, Elaine S.

AU - Smith, Mark E.

AU - Sikorski, James A.

PY - 2000/11/1

Y1 - 2000/11/1

UR - http://pubs.acs.org/doi/abs/10.1021/jm000337b

U2 - 10.1021/jm000337b

DO - 10.1021/jm000337b

M3 - Article

VL - 43

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

ER -

Discovery of chiral N, N-disubstituted trifluoro-3-amino-2-propanols as potent inhibitors of cholesteryl ester transfer protein

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