Correlation of Bilayer Membrane Cation Transport and Biological Activity in Alkyl-Substituted Lariat Ethers

W. Matthew Leevy; Michelle E. Weber; Michael R. Gokel; George B. Hughes-Strange; David D. Daranciang; Riccardo Ferdani; George W. Gokel

doi:10.1039/b418194h

Correlation of Bilayer Membrane Cation Transport and Biological Activity in Alkyl-Substituted Lariat Ethers

W. Matthew Leevy
, Michelle E. Weber
, Michael R. Gokel
, George B. Hughes-Strange
, David D. Daranciang
, Riccardo Ferdani
, George W. Gokel

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Organic and Biomolecular Chemistry
Volume	3
DOIs	https://doi.org/10.1039/b418194h
State	Published - Jan 1 2005
Externally published	Yes

Disciplines

Biochemistry
Organic Chemistry

Access to Document

10.1039/b418194hLicense: Unspecified

Cite this

@article{2641bb8a09894300b572f84495837088,

title = "Correlation of Bilayer Membrane Cation Transport and Biological Activity in Alkyl-Substituted Lariat Ethers",

author = "Leevy, \{W. Matthew\} and Weber, \{Michelle E.\} and Gokel, \{Michael R.\} and Hughes-Strange, \{George B.\} and Daranciang, \{David D.\} and Riccardo Ferdani and Gokel, \{George W.\}",

note = "Dialkyldiaza-18-crown-6 lariat ethers having twin n-octyl, n-decyl, n-dodecyl, n-tetradecyl, n-hexadecyl, 1-oxodecyl and 1-oxododecyl side arms were prepared and studied. Cation transport in liposomes mediated by these compounds showed discontinuous activity that correlated with toxicity to the bacteria E. coli and B. Subtilis, and theyeast S. Cerevisiae.",

year = "2005",

month = jan,

day = "1",

doi = "10.1039/b418194h",

language = "American English",

volume = "3",

journal = "Organic and Biomolecular Chemistry",

}

TY - JOUR

T1 - Correlation of Bilayer Membrane Cation Transport and Biological Activity in Alkyl-Substituted Lariat Ethers

AU - Leevy, W. Matthew

AU - Weber, Michelle E.

AU - Gokel, Michael R.

AU - Hughes-Strange, George B.

AU - Daranciang, David D.

AU - Ferdani, Riccardo

AU - Gokel, George W.

N1 - Dialkyldiaza-18-crown-6 lariat ethers having twin n-octyl, n-decyl, n-dodecyl, n-tetradecyl, n-hexadecyl, 1-oxodecyl and 1-oxododecyl side arms were prepared and studied. Cation transport in liposomes mediated by these compounds showed discontinuous activity that correlated with toxicity to the bacteria E. coli and B. Subtilis, and theyeast S. Cerevisiae.

PY - 2005/1/1

Y1 - 2005/1/1

UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615582/

U2 - 10.1039/b418194h

DO - 10.1039/b418194h

M3 - Article

VL - 3

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

ER -

Correlation of Bilayer Membrane Cation Transport and Biological Activity in Alkyl-Substituted Lariat Ethers

Disciplines

Access to Document

Other files and links

Cite this