Chiral N, N-disubstituted trifluoro-3-amino-2-propanols are potent inhibitors of cholesteryl ester transfer protein

Richard C. Durley; Margaret L. Grapperhaus; Brian S. Hickory; Mark A. Massa; Jane L. Wang; Dale P. Spangler; Deborah A. Mischke; Barry L. Parnas; Yvette M. Fobian; Nigam P. Rath; Dorothy D. Honda; Ming Zeng; Daniel T. Connolly; Deborah M. Heuvelman; Bryan J. Witherbee; Michele A. Melton; Kevin C. Glenn; Elaine S. Krul; Mark E. Smith; James A. Sikorski

doi:10.1021/jm020038h

Chiral N, N-disubstituted trifluoro-3-amino-2-propanols are potent inhibitors of cholesteryl ester transfer protein

Richard C. Durley, Margaret L. Grapperhaus, Brian S. Hickory, Mark A. Massa, Jane L. Wang, Dale P. Spangler, Deborah A. Mischke, Barry L. Parnas, Yvette M. Fobian, Nigam P. Rath, Dorothy D. Honda, Ming Zeng, Daniel T. Connolly, Deborah M. Heuvelman, Bryan J. Witherbee, Michele A. Melton, Kevin C. Glenn, Elaine S. Krul, Mark E. Smith, James A. Sikorski

University of Missouri-St. Louis

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Journal of Medicinal Chemistry
Volume	45
DOIs	https://doi.org/10.1021/jm020038h
State	Published - Aug 1 2002

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Biochemistry
Organic Chemistry

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Durley, R. C., Grapperhaus, M. L., Hickory, B. S., Massa, M. A., Wang, J. L., Spangler, D. P., Mischke, D. A., Parnas, B. L., Fobian, Y. M., Rath, N. P., Honda, D. D., Zeng, M., Connolly, D. T., Heuvelman, D. M., Witherbee, B. J., Melton, M. A., Glenn, K. C., Krul, E. S., Smith, M. E., & Sikorski, J. A. (2002). Chiral N, N-disubstituted trifluoro-3-amino-2-propanols are potent inhibitors of cholesteryl ester transfer protein. Journal of Medicinal Chemistry, 45. https://doi.org/10.1021/jm020038h

Durley, RC, Grapperhaus, ML, Hickory, BS, Massa, MA, Wang, JL, Spangler, DP, Mischke, DA, Parnas, BL, Fobian, YM, Rath, NP, Honda, DD, Zeng, M, Connolly, DT, Heuvelman, DM, Witherbee, BJ, Melton, MA, Glenn, KC, Krul, ES, Smith, ME & Sikorski, JA 2002, 'Chiral N, N-disubstituted trifluoro-3-amino-2-propanols are potent inhibitors of cholesteryl ester transfer protein', Journal of Medicinal Chemistry, vol. 45. https://doi.org/10.1021/jm020038h

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title = "Chiral N, N-disubstituted trifluoro-3-amino-2-propanols are potent inhibitors of cholesteryl ester transfer protein",

author = "Durley, {Richard C.} and Grapperhaus, {Margaret L.} and Hickory, {Brian S.} and Massa, {Mark A.} and Wang, {Jane L.} and Spangler, {Dale P.} and Mischke, {Deborah A.} and Parnas, {Barry L.} and Fobian, {Yvette M.} and Rath, {Nigam P.} and Honda, {Dorothy D.} and Ming Zeng and Connolly, {Daniel T.} and Heuvelman, {Deborah M.} and Witherbee, {Bryan J.} and Melton, {Michele A.} and Glenn, {Kevin C.} and Krul, {Elaine S.} and Smith, {Mark E.} and Sikorski, {James A.}",

note = "J Med Chem. 2002 Aug 29;45(18):3891-904.",

year = "2002",

month = aug,

day = "1",

doi = "10.1021/jm020038h",

language = "American English",

volume = "45",

journal = "Journal of Medicinal Chemistry",

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TY - JOUR

T1 - Chiral N, N-disubstituted trifluoro-3-amino-2-propanols are potent inhibitors of cholesteryl ester transfer protein

AU - Durley, Richard C.

AU - Grapperhaus, Margaret L.

AU - Hickory, Brian S.

AU - Massa, Mark A.

AU - Wang, Jane L.

AU - Spangler, Dale P.

AU - Mischke, Deborah A.

AU - Parnas, Barry L.

AU - Fobian, Yvette M.

AU - Rath, Nigam P.

AU - Honda, Dorothy D.

AU - Zeng, Ming

AU - Connolly, Daniel T.

AU - Heuvelman, Deborah M.

AU - Witherbee, Bryan J.

AU - Melton, Michele A.

AU - Glenn, Kevin C.

AU - Krul, Elaine S.

AU - Smith, Mark E.

AU - Sikorski, James A.

N1 - J Med Chem. 2002 Aug 29;45(18):3891-904.

PY - 2002/8/1

Y1 - 2002/8/1

UR - https://www.ncbi.nlm.nih.gov/pubmed/12190312

U2 - 10.1021/jm020038h

DO - 10.1021/jm020038h

M3 - Article

VL - 45

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

ER -

Chiral N, N-disubstituted trifluoro-3-amino-2-propanols are potent inhibitors of cholesteryl ester transfer protein

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