Chemical synthesis of human milk oligosaccharides: lacto-N-neohexaose (Galβ1 → 4GlcNAcβ1→)2 3,6Galβ1 → 4Glc.

Mithila D. Bandara; Keith J. Stine; Alexei V. Demchenko

doi:10.1039/D0OB00172D

Chemical synthesis of human milk oligosaccharides: lacto-N-neohexaose (Galβ1 → 4GlcNAcβ1→)2 3,6Galβ1 → 4Glc.

Mithila D. Bandara, Keith J. Stine, Alexei V. Demchenko

University of Missouri-St. Louis

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Organic and Biomolecular Chemistry
Volume	18
DOIs	https://doi.org/10.1039/D0OB00172D
State	Published - Mar 4 2020

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Organic Chemistry

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title = "Chemical synthesis of human milk oligosaccharides: lacto-N-neohexaose (Galβ1 → 4GlcNAcβ1→)2 3,6Galβ1 → 4Glc.",

author = "Bandara, {Mithila D.} and Stine, {Keith J.} and Demchenko, {Alexei V.}",

note = "The first chemical synthesis of lacto-N-neohexaose (LNnH) has been completed using a convergent synthetic strategy. The reaction conditions and donor-acceptor combinations have been carefully refined to minimize side reactions and achieve high yields in all glycosylation steps. Lacto-N-neotetraose, another c",

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language = "American English",

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journal = "Organic and Biomolecular Chemistry",

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T1 - Chemical synthesis of human milk oligosaccharides: lacto-N-neohexaose (Galβ1 → 4GlcNAcβ1→)2 3,6Galβ1 → 4Glc.

AU - Bandara, Mithila D.

AU - Stine, Keith J.

AU - Demchenko, Alexei V.

N1 - The first chemical synthesis of lacto-N-neohexaose (LNnH) has been completed using a convergent synthetic strategy. The reaction conditions and donor-acceptor combinations have been carefully refined to minimize side reactions and achieve high yields in all glycosylation steps. Lacto-N-neotetraose, another c

PY - 2020/3/4

Y1 - 2020/3/4

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UR - https://pubs.rsc.org/en/content/articlelanding/2020/ob/d0ob00172d

U2 - 10.1039/D0OB00172D

DO - 10.1039/D0OB00172D

M3 - Article

VL - 18

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

ER -

Chemical synthesis of human milk oligosaccharides: lacto-N-neohexaose (Galβ1 → 4GlcNAcβ1→)2 3,6Galβ1 → 4Glc.

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