Antiretroviral monocyte efficacy score linked to cognitive impairment in HIV.

Cecilia M Shikuma; Beau Nakamoto; Bruce Shiramizu; Chin-Yuan Liang; Victor DeGruttola; Kara Bennett; Robert Paul; Kalpana Kallianpur; Dominic Chow; Christina Gavegnano; Selwyn J Hurwitz; Raymond F Schinazi; Victor G Valcour

doi:10.3851/IMP2411

Antiretroviral monocyte efficacy score linked to cognitive impairment in HIV.

Cecilia M Shikuma, Beau Nakamoto, Bruce Shiramizu, Chin-Yuan Liang, Victor DeGruttola, Kara Bennett, Robert Paul, Kalpana Kallianpur, Dominic Chow, Christina Gavegnano, Selwyn J Hurwitz, Raymond F Schinazi, Victor G Valcour

University of Missouri-St. Louis

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Antiviral Therapy
Volume	17
DOIs	https://doi.org/10.3851/IMP2411
State	Published - Jan 1 2012

Disciplines

Virology
Medicine and Health Sciences
Immunology and Infectious Disease

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10.3851/IMP2411License: Unspecified

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@article{8f49d6bc43bf4d5f8f740ed890558480,

title = "Antiretroviral monocyte efficacy score linked to cognitive impairment in HIV.",

author = "Shikuma, \{Cecilia M\} and Beau Nakamoto and Bruce Shiramizu and Chin-Yuan Liang and Victor DeGruttola and Kara Bennett and Robert Paul and Kalpana Kallianpur and Dominic Chow and Christina Gavegnano and Hurwitz, \{Selwyn J\} and Schinazi, \{Raymond F\} and Valcour, \{Victor G\}",

note = "Monocytes transmigrating to the brain play a central role in HIV neuropathology. We hypothesized that the continued existence of neurocognitive impairment (NCI) despite potent antiretroviral (ARV) therapy is mediated by the inability of such therapy to control this monocyte/macrophage reservoir. Cross-sectional and longitudinal analyses were conducted within a prospectively enrolled cohort.",

year = "2012",

month = jan,

day = "1",

doi = "10.3851/IMP2411",

language = "American English",

volume = "17",

journal = "Antiviral Therapy",

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TY - JOUR

T1 - Antiretroviral monocyte efficacy score linked to cognitive impairment in HIV.

AU - Shikuma, Cecilia M

AU - Nakamoto, Beau

AU - Shiramizu, Bruce

AU - Liang, Chin-Yuan

AU - DeGruttola, Victor

AU - Bennett, Kara

AU - Paul, Robert

AU - Kallianpur, Kalpana

AU - Chow, Dominic

AU - Gavegnano, Christina

AU - Hurwitz, Selwyn J

AU - Schinazi, Raymond F

AU - Valcour, Victor G

N1 - Monocytes transmigrating to the brain play a central role in HIV neuropathology. We hypothesized that the continued existence of neurocognitive impairment (NCI) despite potent antiretroviral (ARV) therapy is mediated by the inability of such therapy to control this monocyte/macrophage reservoir. Cross-sectional and longitudinal analyses were conducted within a prospectively enrolled cohort.

PY - 2012/1/1

Y1 - 2012/1/1

UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715550/

U2 - 10.3851/IMP2411

DO - 10.3851/IMP2411

M3 - Article

VL - 17

JO - Antiviral Therapy

JF - Antiviral Therapy

ER -

Antiretroviral monocyte efficacy score linked to cognitive impairment in HIV.

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