A Practical Gram-Scale Synthesis of Acrylohydroxamic Acid

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Abstract

Acrylohydroxamic acid, which is a useful monomer for the preparation of polymeric materials, has been prepared in a straightforward, two-step synthesis from readily available starting materials. The key steps are coupling of acrylic acid with O-tetrahydropyranylhydroxyl amine to provide protection of the hydroxylamine functionality, followed by acid cleavage of the protecting group.
Original languageAmerican English
JournalSynthesis
Volume49
DOIs
StatePublished - Dec 1 2017

Disciplines

  • Organic Chemistry
  • Inorganic Chemistry

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