@article{267a9dc087714d4b921e1ca5acbe87a8,
title = "A Formal Synthesis of the C1-C9 Fragment of Amphidinolide C Employing the Tamaru Reaction",
author = "Paudyal, {Mahesh P.} and Rath, {Nigam P.} and Spilling, {Christopher D.}",
note = "Homoallylation of aldehydes with isoprene and triethyl borane, catalyzed by Ni(acac) 2 gave hydroxy alkenes in good yield with excellent regio- and stereoselectivity. Cross metathesis of the hydroxy alkenes with methyl acrylate using second generation Grubbs catalyst and copper(I) iodide afforded α,β-unsaturated esters, which underwent cyclization in the presence of DBU to produce tetrahydrofurans with the correct relative configuration for C1-C9 fragment of amphidinolide C, C2 and F.",
year = "2010",
month = jul,
day = "2",
doi = "10.1021/ol100959a",
language = "American English",
volume = "12",
journal = "Organic Letters",
}