108. Hippocampal Subfield Volumes Relate to Unique Phenotypes of PTSD: International Analysis by the PGC-ENIGMA PTSD Working Group

Lauren E Salminen; Mark W Logue; Emily L. Dennis; Juan E. Iglesias; Jasmeet Hayes; Soraya Seedat; Steven Bruce; Christopher D. Whelan; Neda Jahanshad; Paul M. Thompson; Rajendra A. Morey

doi:10.1016/j.biopsych.2019.03.122

108. Hippocampal Subfield Volumes Relate to Unique Phenotypes of PTSD: International Analysis by the PGC-ENIGMA PTSD Working Group

Lauren E Salminen, Mark W Logue, Emily L. Dennis, Juan E. Iglesias, Jasmeet Hayes, Soraya Seedat, Steven Bruce, Christopher D. Whelan, Neda Jahanshad, Paul M. Thompson, Rajendra A. Morey

University of Missouri-St. Louis

Research output: Contribution to journal › Article › peer-review

Abstract

Subregions of the hippocampus are cytoarchitecturally and functionally distinct and may be differentially impacted by trauma exposure and PTSD. Here we used a harmonized neuroimaging protocol based on FreeSurfer 6.0 to identify a common hippocampal subfield marker of PTSD across more than 30 cohorts worldwide (PTSD, n=1,211; Control, n=1,782; Mage=38.5(13.6) years).

Original language	American English
Journal	Biological Psychiatry
Volume	85
DOIs	https://doi.org/10.1016/j.biopsych.2019.03.122
State	Published - May 15 2019

Disciplines

Psychiatry
Psychiatric and Mental Health

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Salminen, L. E., Logue, M. W., Dennis, E. L., Iglesias, J. E., Hayes, J., Seedat, S., Bruce, S., Whelan, C. D., Jahanshad, N., Thompson, P. M., & Morey, R. A. (2019). 108. Hippocampal Subfield Volumes Relate to Unique Phenotypes of PTSD: International Analysis by the PGC-ENIGMA PTSD Working Group. Biological Psychiatry, 85. https://doi.org/10.1016/j.biopsych.2019.03.122

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AU - Salminen, Lauren E

AU - Logue, Mark W

AU - Dennis, Emily L.

AU - Iglesias, Juan E.

AU - Hayes, Jasmeet

AU - Seedat, Soraya

AU - Bruce, Steven

AU - Whelan, Christopher D.

AU - Jahanshad, Neda

AU - Thompson, Paul M.

AU - Morey, Rajendra A.

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N2 - Subregions of the hippocampus are cytoarchitecturally and functionally distinct and may be differentially impacted by trauma exposure and PTSD. Here we used a harmonized neuroimaging protocol based on FreeSurfer 6.0 to identify a common hippocampal subfield marker of PTSD across more than 30 cohorts worldwide (PTSD, n=1,211; Control, n=1,782; Mage=38.5(13.6) years).

AB - Subregions of the hippocampus are cytoarchitecturally and functionally distinct and may be differentially impacted by trauma exposure and PTSD. Here we used a harmonized neuroimaging protocol based on FreeSurfer 6.0 to identify a common hippocampal subfield marker of PTSD across more than 30 cohorts worldwide (PTSD, n=1,211; Control, n=1,782; Mage=38.5(13.6) years).

UR - https://www.biologicalpsychiatryjournal.com/article/S0006-3223(19)30272-0/abstract

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DO - 10.1016/j.biopsych.2019.03.122

M3 - Article

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JO - Biological Psychiatry

JF - Biological Psychiatry

ER -

108. Hippocampal Subfield Volumes Relate to Unique Phenotypes of PTSD: International Analysis by the PGC-ENIGMA PTSD Working Group

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