Personal profile
About
Dr. Nichols received his B.S. degree from Lindenwood College and his Ph.D. from Purdue University. Prior to joining the UMSL faculty in the Fall of 2004, he completed a postdoctoral fellowship at the Mayo Clinic in Jacksonville, FL.
Research Interests
- Alzheimer’s Disease
- Biophysical Analysis of Proteins
- Chromatography
- Light Scattering
- Electron
- Atomic Force
- Confocal Microscopy
- Spectroscopy
- Cell Culture
- Cellular Studies
- Cell Signaling
- Cell-Surface Receptors Elucidation of Inflammatory Pathways
- Biochemical and Biological Techniques
- PAGE
- mRNA Measurements
- and Immunological Techniques
Disciplines
- Biochemistry
- Chemistry
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Development of a Simple and Effective Lipid-A Antagonist Based on Computational Prediction
Slater, O., Dhami, K. B., Shrestha, G., Kontoyianni, M., Nichols, M. & Demchenko, A. V., 2022, In: ACS Infectious Diseases. 8Research output: Contribution to journal › Article › peer-review
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Development of β-sheet structure in Aβ aggregation intermediates diminishes exposed hydrophobic surface area and enhances proinflammatory activity
Dhami, K. B., Karki, S., Parks, A., Nichols, C. G. & Nichols, M., Sep 2022, In: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1870Research output: Contribution to journal › Article › peer-review
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Expression of NLRP3 inflammasome proteins in ExpiCHO‐S mammalian cells reveals oligomerization properties that are highly sensitive to solution conditions
Makoni, N. J., Garrad, E. C., Redzic, A. & Nichols, M., 2021, In: Biotechnology Progress. 37Research output: Contribution to journal › Article › peer-review
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Inhibition of matrix metalloproteinase-9 secretion by dimethyl sulfoxide and cyclic adenosine monophosphate in human monocytes
Denner, D. R., Udan-Johns, M. L. & Nichols, M., Jan 27 2021, In: World Journal of Biological Chemistry. 12Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The intricate biophysical puzzle of caspase-1 activation
Nichols, M. & Makoni, N. J., Mar 15 2021, In: Archives of Biochemistry and Biophysics. 699Research output: Contribution to journal › Article › peer-review